<!--QuoteBegin-->QUOTE<!--QuoteEBegin-->http://www.biomedcentral.com/1471-2156/2/13/comments/comments
.............Recently, Palanichamy et al.(2004) disregarded our interpretation as simplistic and, based on new mitochondrial genome data of macrohaplogroup N in India, supported the more parsimonious hypothesis of a single migration route out of Africa proposed by others (Forster et al. 2001), but with the addition of another lineage, R, to that migration. So a scenario with a single migration route out of Africa and three-founder mtDNA lineages was defined. In a recent article(Tanaka et al. 2004) the weakness of both hypothesis to congruently incorporate new mitochondrial data, mainly from Australia and Papua New Guinea (Ingman and Gyllensten 2003), was discussed suggesting that a new work hypothesis should be formulated to accomodate this recent information. <b>Of main concern was the presence, in high frequencies, of macrohaplogroup N basal lineages in aboriginal Australians contrasting with its paucity in India and its absence in PNG. </b>If, as we proposed, N marks the northern route, how to explain its absence in southeast Asia and PNG, its natural path to Australia? On the other hand, if N was carried along with M in all routes how to explain its paucity in India and its absence in southeast Asia? Not to mention the lack of basal M in western Eurasia..............<!--QuoteEnd--><!--QuoteEEnd-->
still euros are trying to hold out N as their northern route marker, despite pre-nasreen's presence in malaysia and recent work demonstrating deep roots for N in india. M expansion distorted the original N picture.
.............Recently, Palanichamy et al.(2004) disregarded our interpretation as simplistic and, based on new mitochondrial genome data of macrohaplogroup N in India, supported the more parsimonious hypothesis of a single migration route out of Africa proposed by others (Forster et al. 2001), but with the addition of another lineage, R, to that migration. So a scenario with a single migration route out of Africa and three-founder mtDNA lineages was defined. In a recent article(Tanaka et al. 2004) the weakness of both hypothesis to congruently incorporate new mitochondrial data, mainly from Australia and Papua New Guinea (Ingman and Gyllensten 2003), was discussed suggesting that a new work hypothesis should be formulated to accomodate this recent information. <b>Of main concern was the presence, in high frequencies, of macrohaplogroup N basal lineages in aboriginal Australians contrasting with its paucity in India and its absence in PNG. </b>If, as we proposed, N marks the northern route, how to explain its absence in southeast Asia and PNG, its natural path to Australia? On the other hand, if N was carried along with M in all routes how to explain its paucity in India and its absence in southeast Asia? Not to mention the lack of basal M in western Eurasia..............<!--QuoteEnd--><!--QuoteEEnd-->
still euros are trying to hold out N as their northern route marker, despite pre-nasreen's presence in malaysia and recent work demonstrating deep roots for N in india. M expansion distorted the original N picture.