Husky, please don't delete your comments.
It is a sad misfortune that our best people are so careful with their words, and the "populace" have endure the never ending rants of the 4M.
It is also likely that A1 was not a new mutation in the A2 wild type, but rather the wild type present in the Euro aurochs or at least a very old mutation in Europe, and that the A2 allele was a secondary introgression into europe. Such introgression is non-controversial for indic origin zebu in the case of India-to-Africa; we are only too familiar why such would not be considered in the case of Europe.
Since diabetes is a survival trait (a starvation state wherein slow metabolism is maximized), it is very likely that A1 was selected in the euro auroch. Of course, such elementaries elude those for whom creationism is culture - much more occam razory to posit a single population; In this particular case, it was not possible to posit the bovine version of aboriginal (ie normatized) ANI in Europe and ASI in India, since the "mix" is in Europe itself. Thankfully, this autosomal has "survival value" and the direction of introgression is therefore clear.
At any rate, even if this not a case is allele introgression, the (dde-domesticated) A1 mutation's circumscribed distribution also precludes a euro origin for A2.
It is a sad misfortune that our best people are so careful with their words, and the "populace" have endure the never ending rants of the 4M.
It is also likely that A1 was not a new mutation in the A2 wild type, but rather the wild type present in the Euro aurochs or at least a very old mutation in Europe, and that the A2 allele was a secondary introgression into europe. Such introgression is non-controversial for indic origin zebu in the case of India-to-Africa; we are only too familiar why such would not be considered in the case of Europe.
Since diabetes is a survival trait (a starvation state wherein slow metabolism is maximized), it is very likely that A1 was selected in the euro auroch. Of course, such elementaries elude those for whom creationism is culture - much more occam razory to posit a single population; In this particular case, it was not possible to posit the bovine version of aboriginal (ie normatized) ANI in Europe and ASI in India, since the "mix" is in Europe itself. Thankfully, this autosomal has "survival value" and the direction of introgression is therefore clear.
At any rate, even if this not a case is allele introgression, the (dde-domesticated) A1 mutation's circumscribed distribution also precludes a euro origin for A2.