06-10-2012, 12:46 AM
[quote name='dhu' date='09 June 2012 - 10:59 PM' timestamp='1339262514' post='115066']
The selection gradient points to migration of the mutated form of SLC24A5 Out-of-India. The mutation is 100% selective in Europe (along with Lactase persistence). Invariably, 100% selection in any area means that the mutation arose in the opposite where the heterozygotes predominate. There are a number of papers making ridiculous and stretched arguments against the evidence of the selection gradient.
The mutation probably arose in association with leprosy in the Indus Valley.
[/quote]
My earlier post seems to imply that SLC24A5 modern form arose in Tamils, with a 30% ratio, ratio climbing to 50% for Sinhalese and perhaps 75% for Punjabis and 100% in Europeans
The selection gradient points to migration of the mutated form of SLC24A5 Out-of-India. The mutation is 100% selective in Europe (along with Lactase persistence). Invariably, 100% selection in any area means that the mutation arose in the opposite where the heterozygotes predominate. There are a number of papers making ridiculous and stretched arguments against the evidence of the selection gradient.
The mutation probably arose in association with leprosy in the Indus Valley.
[/quote]
My earlier post seems to imply that SLC24A5 modern form arose in Tamils, with a 30% ratio, ratio climbing to 50% for Sinhalese and perhaps 75% for Punjabis and 100% in Europeans