06-10-2012, 01:32 AM
Dhu ji,
Is it possible for you to kindly further explain how does one fix the direction of mutation? for a lay man who has very elementary genetic knowledge, seems like mutation took place in Europe because of the need to adjust to cooler climates, given the peopling happened from Africa to South Asia earlier so one can say that from Sumbrahmanmiam ji's posts above the G->A might have taken place due to a necessity to adjust to a new place, so this might have happened in higher latitude as compared to the Indian subcontinent? am I correct in understanding?
Subrahmanmiam ji:
So threonine allele's presence is because of G->A mutation? wiki only mentions threonine. Are there any references which I refer to about this gradient?
Thanks again.
Quote:100% selection in any area means that the mutation arose in the opposite where the heterozygotes predominate.
Is it possible for you to kindly further explain how does one fix the direction of mutation? for a lay man who has very elementary genetic knowledge, seems like mutation took place in Europe because of the need to adjust to cooler climates, given the peopling happened from Africa to South Asia earlier so one can say that from Sumbrahmanmiam ji's posts above the G->A might have taken place due to a necessity to adjust to a new place, so this might have happened in higher latitude as compared to the Indian subcontinent? am I correct in understanding?
Subrahmanmiam ji:
So threonine allele's presence is because of G->A mutation? wiki only mentions threonine. Are there any references which I refer to about this gradient?
Thanks again.