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What DNA Says About Aryan Invasion Theory-1
#83
Oppenheimer's South-to-North dynamic operated even within Europe itself. It is becoming clearer that Europe was populated through the south via Indic population types moving thru the ME. The last of these settler groups were the gypsies.

European Journal of Human Genetics, May 2003, Volume 11, Number 5

<b>Spatial patterns of cystic fibrosis mutation spectra in European populations</b>
Oscar Lao, et al.

Abstract

Cystic fibrosis (CF) is the most frequent severe recessive disorder in European populations. We have analyzed its mutation frequency spectrum in 94 European, North African and SW Asian populations taken from the literature. Most major mutations as well as the incidence of CF mutations showed clinals patterns as demonstrated by autocorrelogram analysis. More importantly, measures of mutation diversity did also show clinal patterns, with mutation spectra being more diverse in southern than in northern Europe. <b>This increased diversity would imply roughly a three-fold long-term effective population size in southern than in northern Europe.</b> Distances were computed among populations based on their CF mutation frequencies and compared with distances based on other genic regions. CF-based distances correlated with mtDNA but not with Y-chromosome-based distances, which may be a consequence of the relatively homogeneous CF mutation frequencies in European populations.


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